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BDBM50431132 CHEMBL2332080

SMILES: O=C(Nc1ccc(cc1)-c1cn[nH]c1)OCc1ccccc1

InChI Key: InChIKey=FBVPIOMMLDGIAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431132   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))
BDBM50431132
PNG
(CHEMBL2332080)
Show SMILES O=C(Nc1ccc(cc1)-c1cn[nH]c1)OCc1ccccc1
Show InChI InChI=1S/C17H15N3O2/c21-17(22-12-13-4-2-1-3-5-13)20-16-8-6-14(7-9-16)15-10-18-19-11-15/h1-11H,12H2,(H,18,19)(H,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assay


J Med Chem 56: 3568-81 (2013)


Article DOI: 10.1021/jm400062r
BindingDB Entry DOI: 10.7270/Q28C9XMJ
More data for this
Ligand-Target Pair