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SMILES: COc1cccc(CNC(=O)N(CCN2CCCC2)c2ccc(cc2)-c2cn[nH]c2)c1

InChI Key: InChIKey=VICPYUOROOQPTH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431147   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))		BDBM50431147
PNG
(CHEMBL2332095)
Show SMILES COc1cccc(CNC(=O)N(CCN2CCCC2)c2ccc(cc2)-c2cn[nH]c2)c1
Show InChI InChI=1S/C24H29N5O2/c1-31-23-6-4-5-19(15-23)16-25-24(30)29(14-13-28-11-2-3-12-28)22-9-7-20(8-10-22)21-17-26-27-18-21/h4-10,15,17-18H,2-3,11-14,16H2,1H3,(H,25,30)(H,26,27)
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KEGG

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PC sid
UniChem

Similars
Article
PubMed
n/an/a>2.00E+4n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assay

J Med Chem 56: 3568-81 (2013)


Article DOI: 10.1021/jm400062r
BindingDB Entry DOI: 10.7270/Q28C9XMJ
More data for this
Ligand-Target Pair