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SMILES: O=C(Nc1ccccc1)Nc1ccc(cc1)-c1cn[nH]c1

InChI Key: InChIKey=XJHJFSPDEPLSBG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431158   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))		BDBM50431158
PNG
(CHEMBL2332077)
Show SMILES O=C(Nc1ccccc1)Nc1ccc(cc1)-c1cn[nH]c1
Show InChI InChI=1S/C16H14N4O/c21-16(19-14-4-2-1-3-5-14)20-15-8-6-12(7-9-15)13-10-17-18-11-13/h1-11H,(H,17,18)(H2,19,20,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 304n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of ROCK2 (unknown origin) after 4 hrs by HTRF assay

J Med Chem 56: 3568-81 (2013)


Article DOI: 10.1021/jm400062r
BindingDB Entry DOI: 10.7270/Q28C9XMJ
More data for this
Ligand-Target Pair