BDBM50431228 CHEMBL2333023

SMILES: OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccnc1

InChI Key: InChIKey=VEFSZHQQQXLTPA-JTQLQIEISA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50431228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50431228 (CHEMBL2333023) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccnc1 |r| Show InChI InChI=1S/C12H16BN3O4/c17-11(16-6-2-4-10(16)13(19)20)8-15-12(18)9-3-1-5-14-7-9/h1,3,5,7,10,19-20H,2,4,6,8H2,(H,15,18)/t10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University Sackler School of Biomedical Sciences Curated by ChEMBL					Assay Description Inhibition of human PREP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay				J Med Chem 56: 3467-77 (2013) Article DOI: 10.1021/jm400351a BindingDB Entry DOI: 10.7270/Q2C53N7W
					More data for this Ligand-Target Pair
Fibroblast activation protein alpha (Homo sapiens (Human))	BDBM50431228 (CHEMBL2333023) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccnc1 |r| Show InChI InChI=1S/C12H16BN3O4/c17-11(16-6-2-4-10(16)13(19)20)8-15-12(18)9-3-1-5-14-7-9/h1,3,5,7,10,19-20H,2,4,6,8H2,(H,15,18)/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University Sackler School of Biomedical Sciences Curated by ChEMBL					Assay Description Inhibition of human FAP using Z-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay				J Med Chem 56: 3467-77 (2013) Article DOI: 10.1021/jm400351a BindingDB Entry DOI: 10.7270/Q2C53N7W
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50431228 (CHEMBL2333023) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccnc1 |r| Show InChI InChI=1S/C12H16BN3O4/c17-11(16-6-2-4-10(16)13(19)20)8-15-12(18)9-3-1-5-14-7-9/h1,3,5,7,10,19-20H,2,4,6,8H2,(H,15,18)/t10-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University Sackler School of Biomedical Sciences Curated by ChEMBL					Assay Description Inhibition of human DPP4 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay				J Med Chem 56: 3467-77 (2013) Article DOI: 10.1021/jm400351a BindingDB Entry DOI: 10.7270/Q2C53N7W
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50431228 (CHEMBL2333023) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccnc1 |r| Show InChI InChI=1S/C12H16BN3O4/c17-11(16-6-2-4-10(16)13(19)20)8-15-12(18)9-3-1-5-14-7-9/h1,3,5,7,10,19-20H,2,4,6,8H2,(H,15,18)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University Sackler School of Biomedical Sciences Curated by ChEMBL					Assay Description Inhibition of human DPP8 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay				J Med Chem 56: 3467-77 (2013) Article DOI: 10.1021/jm400351a BindingDB Entry DOI: 10.7270/Q2C53N7W
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50431228 (CHEMBL2333023) Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC(=O)c1cccnc1 |r| Show InChI InChI=1S/C12H16BN3O4/c17-11(16-6-2-4-10(16)13(19)20)8-15-12(18)9-3-1-5-14-7-9/h1,3,5,7,10,19-20H,2,4,6,8H2,(H,15,18)/t10-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Tufts University Sackler School of Biomedical Sciences Curated by ChEMBL					Assay Description Inhibition of human DPP9 using H-Gly-Pro-AMC as substrate preincubated for 10 mins prior to substrate addition by fluorescence assay				J Med Chem 56: 3467-77 (2013) Article DOI: 10.1021/jm400351a BindingDB Entry DOI: 10.7270/Q2C53N7W
					More data for this Ligand-Target Pair