BindingDB logo
myBDB logout

null

SMILES: Cn1c2cc(Br)ccc2c2nc([nH]c2c1=O)-c1ccccc1Cl

InChI Key: InChIKey=RLPACHZKSYBGNK-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431409   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E synthase


(Homo sapiens (Human))		BDBM50431409
PNG
(CHEMBL2348042)
Show SMILES Cn1c2cc(Br)ccc2c2nc([nH]c2c1=O)-c1ccccc1Cl
Show InChI InChI=1S/C17H11BrClN3O/c1-22-13-8-9(18)6-7-11(13)14-15(17(22)23)21-16(20-14)10-4-2-3-5-12(10)19/h2-8H,1H3,(H,20,21)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 85n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of mPGES1 (unknown origin) transfected in HEK293 cells co-expressing COX1 using arachidonic acid as substrate assessed as inhibition of PG...

Bioorg Med Chem 21: 2068-78 (2013)


Article DOI: 10.1016/j.bmc.2013.01.018
BindingDB Entry DOI: 10.7270/Q2XW4M55
More data for this
Ligand-Target Pair