null
SMILES: Clc1ccccc1-c1nc2c([nH]1)c(=S)[nH]c1cc(Br)ccc21
InChI Key: InChIKey=MTNKABNXGMLEGU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50431412 (CHEMBL2348039) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma Co., Ltd Curated by ChEMBL | Assay Description Inhibition of mPGES1 (unknown origin) transfected in HEK293 cells co-expressing COX1 using arachidonic acid as substrate assessed as inhibition of PG... | Bioorg Med Chem 21: 2068-78 (2013) Article DOI: 10.1016/j.bmc.2013.01.018 BindingDB Entry DOI: 10.7270/Q2XW4M55 | |||||||||||
More data for this Ligand-Target Pair |