BDBM50431923 5‐chloro‐2‐(naphthalen‐2‐yloxy)phenol (30)::CHEMBL2347845

SMILES: Oc1cc(Cl)ccc1Oc1ccc2ccccc2c1

InChI Key: InChIKey=PDNCXSWHFTWSBA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50431923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-acyl carrier reductase (Toxoplasma gondii)	BDBM50431923 (5‐chloro‐2‐(naphthalen‐2&#...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc2ccccc2c1 Show InChI InChI=1S/C16H11ClO2/c17-13-6-8-16(15(18)10-13)19-14-7-5-11-3-1-2-4-12(11)9-14/h1-10,18H	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of Toxoplasma gondii enoyl reductase assessed as conversion of trans-2-acyl-ACP to acyl-ACP				Bioorg Med Chem Lett 23: 2035-43 (2013) Article DOI: 10.1016/j.bmcl.2013.02.019 BindingDB Entry DOI: 10.7270/Q29Z968J
					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase (Toxoplasma gondii)	BDBM50431923 (5‐chloro‐2‐(naphthalen‐2&#...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc2ccccc2c1 Show InChI InChI=1S/C16H11ClO2/c17-13-6-8-16(15(18)10-13)19-14-7-5-11-3-1-2-4-12(11)9-14/h1-10,18H	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	7.5	n/a
Johns Hopkins Bloomberg School of Public Health					Assay Description The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...				Biochemistry 52: 9155-66 (2013) Article DOI: 10.1021/bi400945y BindingDB Entry DOI: 10.7270/Q2PV6J27
					More data for this Ligand-Target Pair