BDBM50431935 CHEMBL2348073

SMILES: OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=AMEDLCPVIJTCOD-WOJGMQOQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50431935 (CHEMBL2348073) Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C21H16N2O3S2/c24-17-12-27-18(22-17)11-19-23-21(16(28-19)10-20(25)26)15-8-6-14(7-9-15)13-4-2-1-3-5-13/h1-9,11H,10,12H2,(H,22,24)(H,25,26)/b18-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Asahi Kasei Pharma Corporation Curated by ChEMBL					Assay Description Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET method				Bioorg Med Chem Lett 23: 2106-10 (2013) Article DOI: 10.1016/j.bmcl.2013.01.121 BindingDB Entry DOI: 10.7270/Q26974ZF
					More data for this Ligand-Target Pair