BDBM50431997 CHEMBL2348723

SMILES: CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12

InChI Key: InChIKey=LUGGYQMGVDEADM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50431997   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50431997 (CHEMBL2348723) Show SMILES CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C12H13N3O2/c1-7(2)11(16)13-10-8-5-3-4-6-9(8)12(17)15-14-10/h3-7H,1-2H3,(H,15,17)(H,13,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of human recombinant CDK5/p25 after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP				Bioorg Med Chem Lett 23: 2007-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.027 BindingDB Entry DOI: 10.7270/Q2T1551T
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)	BDBM50431997 (CHEMBL2348723) Show SMILES CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C12H13N3O2/c1-7(2)11(16)13-10-8-5-3-4-6-9(8)12(17)15-14-10/h3-7H,1-2H3,(H,15,17)(H,13,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate after 30 mins by scintillation counting an...				Bioorg Med Chem Lett 23: 2007-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.027 BindingDB Entry DOI: 10.7270/Q2T1551T
					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Sus scrofa)	BDBM50431997 (CHEMBL2348723) Show SMILES CC(C)C(=O)Nc1n[nH]c(=O)c2ccccc12 Show InChI InChI=1S/C12H13N3O2/c1-7(2)11(16)13-10-8-5-3-4-6-9(8)12(17)15-14-10/h3-7H,1-2H3,(H,15,17)(H,13,14,16)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of pig brain CK1 using RRKHAAIGpSAYSITA as substrate after 30 mins by scintillation counting analysis in presence of [gamma-33P]ATP				Bioorg Med Chem Lett 23: 2007-13 (2013) Article DOI: 10.1016/j.bmcl.2013.02.027 BindingDB Entry DOI: 10.7270/Q2T1551T
					More data for this Ligand-Target Pair