BDBM50432114 CHEMBL2349574

SMILES: O=C(Nc1cccc(Nc2nnn[nH]2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1

InChI Key: InChIKey=YOWBLAXDEDMBCQ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50432114 (CHEMBL2349574) Show SMILES O=C(Nc1cccc(Nc2nnn[nH]2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 Show InChI InChI=1S/C29H34N8O2/c38-29(31-26-13-7-12-25(22-26)30-28-32-34-35-33-28)37(17-16-36-18-20-39-21-19-36)15-14-27(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-13,22,27H,14-21H2,(H,31,38)(H2,30,32,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Galapagos SASU Curated by ChEMBL					Assay Description Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 2451-4 (2013) Article DOI: 10.1016/j.bmcl.2013.01.078 BindingDB Entry DOI: 10.7270/Q2930VJZ
					More data for this Ligand-Target Pair