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BDBM50432121 CHEMBL2349601

SMILES: O=C(Nc1cccc(c1)-c1cccnc1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1

InChI Key: InChIKey=LKLSIUSCBYEVGV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432121   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50432121
PNG
(CHEMBL2349601)
Show SMILES O=C(Nc1cccc(c1)-c1cccnc1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1
Show InChI InChI=1S/C33H36N4O2/c38-33(35-31-15-7-13-29(25-31)30-14-8-17-34-26-30)37(20-19-36-21-23-39-24-22-36)18-16-32(27-9-3-1-4-10-27)28-11-5-2-6-12-28/h1-15,17,25-26,32H,16,18-24H2,(H,35,38)
PDB

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 200n/an/an/an/a



Galapagos SASU

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay


Bioorg Med Chem Lett 23: 2451-4 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.078
BindingDB Entry DOI: 10.7270/Q2930VJZ
More data for this
Ligand-Target Pair