BDBM50432150 CHEMBL2346784

SMILES: COC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CC(=O)OC(C)(C)C)c1

InChI Key: InChIKey=PYYDFZLYFSWBRU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50432150 (CHEMBL2346784) Show SMILES COC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CC(=O)OC(C)(C)C)c1 Show InChI InChI=1S/C30H34N2O5/c1-30(2,3)37-27(33)21-32(29(35)31-25-17-11-16-24(20-25)28(34)36-4)19-18-26(22-12-7-5-8-13-22)23-14-9-6-10-15-23/h5-17,20,26H,18-19,21H2,1-4H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
Galapagos SASU Curated by ChEMBL					Assay Description Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 2451-4 (2013) Article DOI: 10.1016/j.bmcl.2013.01.078 BindingDB Entry DOI: 10.7270/Q2930VJZ
					More data for this Ligand-Target Pair