BDBM50432161 CHEMBL2346774

SMILES: O=C(NCCC(c1ccccc1)c1ccccc1)Nc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=OBNCRHQEPUHSQY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium-sensing receptor (CaSR) (Homo sapiens (Human))	BDBM50432161 (CHEMBL2346774) Show SMILES O=C(NCCC(c1ccccc1)c1ccccc1)Nc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C28H26N2O/c31-28(30-26-18-16-23(17-19-26)22-10-4-1-5-11-22)29-21-20-27(24-12-6-2-7-13-24)25-14-8-3-9-15-25/h1-19,27H,20-21H2,(H2,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
Galapagos SASU Curated by ChEMBL					Assay Description Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 2451-4 (2013) Article DOI: 10.1016/j.bmcl.2013.01.078 BindingDB Entry DOI: 10.7270/Q2930VJZ
					More data for this Ligand-Target Pair