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BDBM50432162 1-(3,3-diphenylpropyl)-3-p-tolylurea::CHEMBL2346773

SMILES: Cc1ccc(NC(=O)NCCC(c2ccccc2)c2ccccc2)cc1

InChI Key: InChIKey=XSEUVUWDJOYAHO-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432162   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50432162
PNG
(1-(3,3-diphenylpropyl)-3-p-tolylurea | CHEMBL23467...)
Show SMILES Cc1ccc(NC(=O)NCCC(c2ccccc2)c2ccccc2)cc1
Show InChI InChI=1S/C23H24N2O/c1-18-12-14-21(15-13-18)25-23(26)24-17-16-22(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-15,22H,16-17H2,1H3,(H2,24,25,26)
PDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 4.00E+3n/an/an/an/a



Galapagos SASU

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human CaSR transfected in CHO cells after 5 hrs by luciferase reporter gene assay


Bioorg Med Chem Lett 23: 2451-4 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.078
BindingDB Entry DOI: 10.7270/Q2930VJZ
More data for this
Ligand-Target Pair