BDBM50432409 CHEMBL2348999

SMILES: Cn1nncc1C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1

InChI Key: InChIKey=PIVWTDLCYYQCPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50432409 (CHEMBL2348999) Show SMILES Cn1nncc1C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)C4CC4)cn3n2)c1 Show InChI InChI=1S/C20H18N8O3/c1-27-15(10-21-26-27)20(30)22-13-3-2-4-14(9-13)31-18-8-7-17-23-16(11-28(17)25-18)24-19(29)12-5-6-12/h2-4,7-12H,5-6H2,1H3,(H,22,30)(H,24,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using biotinylated poly(Glu:Tyr) as substrate after 5 mins by AlphaScreen assay in presence of 10 uM of ATP				Bioorg Med Chem 21: 2333-45 (2013) Article DOI: 10.1016/j.bmc.2013.01.074 BindingDB Entry DOI: 10.7270/Q22B90C1
					More data for this Ligand-Target Pair