BDBM50432414 CHEMBL2349004

SMILES: O=C(Nc1cn2nc(Oc3cccc(NC(=O)C4CC4)c3)ccc2n1)C1CC1

InChI Key: InChIKey=VHLUMRPXORICSP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50432414 (CHEMBL2349004) Show SMILES O=C(Nc1cn2nc(Oc3cccc(NC(=O)C4CC4)c3)ccc2n1)C1CC1 Show InChI InChI=1S/C20H19N5O3/c26-19(12-4-5-12)21-14-2-1-3-15(10-14)28-18-9-8-17-22-16(11-25(17)24-18)23-20(27)13-6-7-13/h1-3,8-13H,4-7H2,(H,21,26)(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using biotinylated poly(Glu:Tyr) as substrate after 5 mins by AlphaScreen assay in presence of 10 uM of ATP				Bioorg Med Chem 21: 2333-45 (2013) Article DOI: 10.1016/j.bmc.2013.01.074 BindingDB Entry DOI: 10.7270/Q22B90C1
					More data for this Ligand-Target Pair