BDBM50432416 CHEMBL2349007

SMILES: Fc1cccc(c1)C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)c4ccc(cc4)C(F)(F)F)cn3n2)c1

InChI Key: InChIKey=NXHZYGFQXFWFAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50432416 (CHEMBL2349007) Show SMILES Fc1cccc(c1)C(=O)Nc1cccc(Oc2ccc3nc(NC(=O)c4ccc(cc4)C(F)(F)F)cn3n2)c1 Show InChI InChI=1S/C27H17F4N5O3/c28-19-4-1-3-17(13-19)26(38)32-20-5-2-6-21(14-20)39-24-12-11-23-33-22(15-36(23)35-24)34-25(37)16-7-9-18(10-8-16)27(29,30)31/h1-15H,(H,32,38)(H,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Limited Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using biotinylated poly(Glu:Tyr) as substrate after 5 mins by AlphaScreen assay in presence of 10 uM of ATP				Bioorg Med Chem 21: 2333-45 (2013) Article DOI: 10.1016/j.bmc.2013.01.074 BindingDB Entry DOI: 10.7270/Q22B90C1
					More data for this Ligand-Target Pair