BDBM50432686 CHEMBL2347963
SMILES: CN(C)CCC(=O)Nc1cccc(c1)-c1c(oc2ncnc(N[C@H](CO)c3ccccc3)c12)-c1ccccc1
InChI Key: InChIKey=ASCVQXWPIHGQIB-RUZDIDTESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Epidermal growth factor receptor (Homo sapiens (Human)) | BDBM50432686 (CHEMBL2347963) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
National Health Research Institutes Curated by ChEMBL | Assay Description Inhibition of human wild type GST-tagged EGFR kinase domain expressed in Sf9 cells by luminescence assay | J Med Chem 56: 3889-903 (2013) Article DOI: 10.1021/jm400072p BindingDB Entry DOI: 10.7270/Q27W6DJ5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |