BDBM50432900 CHEMBL2376852

SMILES: CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1

InChI Key: InChIKey=TXOPGRNEWKXQBG-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50432900   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily A member 1 (Rattus norvegicus)	BDBM50432900 (CHEMBL2376852) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)10-12-6-8-13(9-7-12)14-4-3-5-15(11-14)17(19)25/h3-9,11H,10H2,1-2H3,(H2,19,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at rat TRPA1 receptor expressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular Ca2+ elevati...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50432900 (CHEMBL2376852) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)10-12-6-8-13(9-7-12)14-4-3-5-15(11-14)17(19)25/h3-9,11H,10H2,1-2H3,(H2,19,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of MAGL (unknown origin) expressed in African green monkey COS7 cell cytosolic fraction assessed as [3H]2-AG hydrolysis to [3H]arachidonic...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50432900 (CHEMBL2376852) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)10-12-6-8-13(9-7-12)14-4-3-5-15(11-14)17(19)25/h3-9,11H,10H2,1-2H3,(H2,19,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 receptor expressed in HEK293 cells assessed as inhibition of capsaicin-induced intracellular Ca2+ elevation incuba...				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50432900 (CHEMBL2376852) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)10-12-6-8-13(9-7-12)14-4-3-5-15(11-14)17(19)25/h3-9,11H,10H2,1-2H3,(H2,19,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Sapienza Universit£ di Roma Curated by ChEMBL					Assay Description Inhibition of FAAH in rat brain membranes assessed as [14C]AEA hydrolysis to [14C]Ethanolamine after 30 mins by scintillation counting analysis				Eur J Med Chem 63: 118-32 (2013) Article DOI: 10.1016/j.ejmech.2013.02.005 BindingDB Entry DOI: 10.7270/Q2K64KFB
					More data for this Ligand-Target Pair