null
SMILES: Cc1cc(SSc2cc(C)nn2-c2ccccc2)n(n1)-c1ccccc1
InChI Key: InChIKey=NIJWTRSAOSNCDN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity immunoglobulin gamma Fc receptor I (Homo sapiens (Human)) | BDBM50432926 (CHEMBL2377172) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Toronto General Research Institute Curated by ChEMBL | Assay Description Inhibition of FCgamma receptor in human PBMC assessed as inhibition of opsonized RBC phagocytosis incubated for 1 hr prior to RBC addition measured a... | Bioorg Med Chem Lett 23: 2324-7 (2013) Article DOI: 10.1016/j.bmcl.2013.02.064 BindingDB Entry DOI: 10.7270/Q2FF3TQM | |||||||||||
More data for this Ligand-Target Pair |