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SMILES: Cc1cc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)no1

InChI Key: InChIKey=SOBOOXUVZQHWOO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50432953   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Extracellular calcium-sensing receptor


(Homo sapiens (Human))		BDBM50432953
PNG
(CHEMBL2377732)
Show SMILES Cc1cc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)no1
Show InChI InChI=1S/C26H32N4O3/c1-21-20-25(28-33-21)27-26(31)30(15-14-29-16-18-32-19-17-29)13-12-24(22-8-4-2-5-9-22)23-10-6-3-7-11-23/h2-11,20,24H,12-19H2,1H3,(H,27,28,31)
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n/an/an/an/a 200n/an/an/an/a



Galapagos SASU

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep...

Bioorg Med Chem Lett 23: 2455-9 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.077
BindingDB Entry DOI: 10.7270/Q228090Q
More data for this
Ligand-Target Pair