null
SMILES: O=C(Nc1nccc(n1)-c1nccs1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1
InChI Key: InChIKey=ORUOLRHRKNXXRV-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Extracellular calcium-sensing receptor (Homo sapiens (Human)) | BDBM50432955 (CHEMBL2377730) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Galapagos SASU Curated by ChEMBL | Assay Description Positive allosteric modulation of human CaSR expressed in CHO cells assessed as increase in intracellular calcium level after 5 hrs by luciferase rep... | Bioorg Med Chem Lett 23: 2455-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.077 BindingDB Entry DOI: 10.7270/Q228090Q | |||||||||||
More data for this Ligand-Target Pair |