BindingDB logo
myBDB logout

null

SMILES: O=C(CCc1coc2cccc(OCC3CCCCC3)c2c1=O)c1ccc(cc1)C#N

InChI Key: InChIKey=VKAGDSVLRSNLDN-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433113   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Interleukin-5


(Mus musculus)		BDBM50433113
PNG
(CHEMBL2377402)
Show SMILES O=C(CCc1coc2cccc(OCC3CCCCC3)c2c1=O)c1ccc(cc1)C#N
Show InChI InChI=1S/C26H25NO4/c27-15-18-9-11-20(12-10-18)22(28)14-13-21-17-31-24-8-4-7-23(25(24)26(21)29)30-16-19-5-2-1-3-6-19/h4,7-12,17,19H,1-3,5-6,13-14,16H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition interleukin-5 in mouse Y16 cells after 48 hrs by WST-1 assay

Bioorg Med Chem 21: 2543-50 (2013)


Article DOI: 10.1016/j.bmc.2013.02.037
BindingDB Entry DOI: 10.7270/Q2RR20MV
More data for this
Ligand-Target Pair