BDBM50433357 CHEMBL2376800

SMILES: CCc1cnc2c(nc(N)nc2c1)N1CC(C1)NC

InChI Key: InChIKey=PREVTMRNRJIUDH-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50433357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 Receptor (Mus musculus (mouse))	BDBM50433357 (CHEMBL2376800) Show SMILES CCc1cnc2c(nc(N)nc2c1)N1CC(C1)NC Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Binding affinity to mouse histamine H4 receptor				Bioorg Med Chem Lett 23: 2663-70 (2013) Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11
					More data for this Ligand-Target Pair
Histamine H4 Receptor (Rattus norvegicus (rat))	BDBM50433357 (CHEMBL2376800) Show SMILES CCc1cnc2c(nc(N)nc2c1)N1CC(C1)NC Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Binding affinity to rat histamine H4 receptor				Bioorg Med Chem Lett 23: 2663-70 (2013) Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50433357 (CHEMBL2376800) Show SMILES CCc1cnc2c(nc(N)nc2c1)N1CC(C1)NC Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H2 receptor expressed in HEK cells				Bioorg Med Chem Lett 23: 2663-70 (2013) Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50433357 (CHEMBL2376800) Show SMILES CCc1cnc2c(nc(N)nc2c1)N1CC(C1)NC Show InChI InChI=1S/C13H18N6/c1-3-8-4-10-11(16-5-8)12(18-13(14)17-10)19-6-9(7-19)15-2/h4-5,9,15H,3,6-7H2,1-2H3,(H2,14,17,18)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.39E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H1 receptor expressed in HEK cells				Bioorg Med Chem Lett 23: 2663-70 (2013) Article DOI: 10.1016/j.bmcl.2013.02.091 BindingDB Entry DOI: 10.7270/Q2K35W11
					More data for this Ligand-Target Pair