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BDBM50433472 CHEMBL2381069

SMILES: Fc1ccccc1CSC(=O)NCCCCCCc1ccccc1

InChI Key: InChIKey=UHUVJMZFLFMMLG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433472   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lipoprotein lipase


(Homo sapiens (Human))
BDBM50433472
PNG
(CHEMBL2381069)
Show SMILES Fc1ccccc1CSC(=O)NCCCCCCc1ccccc1
Show InChI InChI=1S/C20H24FNOS/c21-19-14-8-7-13-18(19)16-24-20(23)22-15-9-2-1-4-10-17-11-5-3-6-12-17/h3,5-8,11-14H,1-2,4,9-10,15-16H2,(H,22,23)
PDB

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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.69E+3n/an/an/an/an/an/a



Janssen Research and Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of human LPL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometry


Bioorg Med Chem Lett 23: 2595-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.113
More data for this
Ligand-Target Pair
Endothelial lipase (EL)


(Mus musculus (Mouse))
BDBM50433472
PNG
(CHEMBL2381069)
Show SMILES Fc1ccccc1CSC(=O)NCCCCCCc1ccccc1
Show InChI InChI=1S/C20H24FNOS/c21-19-14-8-7-13-18(19)16-24-20(23)22-15-9-2-1-4-10-17-11-5-3-6-12-17/h3,5-8,11-14H,1-2,4,9-10,15-16H2,(H,22,23)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 680n/an/an/an/an/an/a



Janssen Research and Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of mouse EL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometry


Bioorg Med Chem Lett 23: 2595-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.113
More data for this
Ligand-Target Pair
Hepatic Lipase (HL)


(Homo sapiens (Human))
BDBM50433472
PNG
(CHEMBL2381069)
Show SMILES Fc1ccccc1CSC(=O)NCCCCCCc1ccccc1
Show InChI InChI=1S/C20H24FNOS/c21-19-14-8-7-13-18(19)16-24-20(23)22-15-9-2-1-4-10-17-11-5-3-6-12-17/h3,5-8,11-14H,1-2,4,9-10,15-16H2,(H,22,23)
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.36E+3n/an/an/an/an/an/a



Janssen Research and Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of human HL expressed in HEK293 cells using PED-A1 as substrate by spectrophotometry


Bioorg Med Chem Lett 23: 2595-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.02.113
More data for this
Ligand-Target Pair