BDBM50433760 CHEMBL2381599

SMILES: NCCCNc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=KMDZJODRFCWAPG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50433760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50433760 (CHEMBL2381599) Show SMILES NCCCNc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClN6O/c17-11-4-2-10(3-5-11)12-9-23-13(14(19)24)8-21-15(16(23)22-12)20-7-1-6-18/h2-5,8-9H,1,6-7,18H2,(H2,19,24)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant MK2				Bioorg Med Chem Lett 23: 2863-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.100 BindingDB Entry DOI: 10.7270/Q2Z60QFW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50433760 (CHEMBL2381599) Show SMILES NCCCNc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClN6O/c17-11-4-2-10(3-5-11)12-9-23-13(14(19)24)8-21-15(16(23)22-12)20-7-1-6-18/h2-5,8-9H,1,6-7,18H2,(H2,19,24)(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CHK1 (unknown origin)				Bioorg Med Chem Lett 23: 2863-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.100 BindingDB Entry DOI: 10.7270/Q2Z60QFW
					More data for this Ligand-Target Pair