Found 2 hits for monomerid = 50433766 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human)) | BDBM50433766
(CHEMBL2381604)Show SMILES NC(=O)c1cnc(N[C@H]2CCCNC2)c2nc(cn12)-c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C22H22N6O/c23-20(29)19-12-25-21(26-17-6-3-9-24-11-17)22-27-18(13-28(19)22)16-8-7-14-4-1-2-5-15(14)10-16/h1-2,4-5,7-8,10,12-13,17,24H,3,6,9,11H2,(H2,23,29)(H,25,26)/t17-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of CHK1 (unknown origin) |
Bioorg Med Chem Lett 23: 2863-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.03.100
BindingDB Entry DOI: 10.7270/Q2Z60QFW |
More data for this
Ligand-Target Pair | |
MAP kinase-activated protein kinase 2
(Homo sapiens (Human)) | BDBM50433766
(CHEMBL2381604)Show SMILES NC(=O)c1cnc(N[C@H]2CCCNC2)c2nc(cn12)-c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C22H22N6O/c23-20(29)19-12-25-21(26-17-6-3-9-24-11-17)22-27-18(13-28(19)22)16-8-7-14-4-1-2-5-15(14)10-16/h1-2,4-5,7-8,10,12-13,17,24H,3,6,9,11H2,(H2,23,29)(H,25,26)/t17-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 910 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MK2 |
Bioorg Med Chem Lett 23: 2863-7 (2013)
Article DOI: 10.1016/j.bmcl.2013.03.100
BindingDB Entry DOI: 10.7270/Q2Z60QFW |
More data for this
Ligand-Target Pair | |
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