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SMILES: NC(=O)c1cnc(Nc2cccnc2)c2nc(cn12)-c1ccc(Cl)cc1

InChI Key: InChIKey=LXWWMTCZURVURW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50433770   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (Human))		BDBM50433770
PNG
(CHEMBL2381597)
Show SMILES NC(=O)c1cnc(Nc2cccnc2)c2nc(cn12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C18H13ClN6O/c19-12-5-3-11(4-6-12)14-10-25-15(16(20)26)9-22-17(18(25)24-14)23-13-2-1-7-21-8-13/h1-10H,(H2,20,26)(H,22,23)
PDB
MMDB

NCI pathway
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PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MK2

Bioorg Med Chem Lett 23: 2863-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.03.100
BindingDB Entry DOI: 10.7270/Q2Z60QFW
More data for this
Ligand-Target Pair