BDBM50434222 CHEMBL2385487

SMILES: ONC(=O)[C@H]1CCCN1S(=O)(=O)CCc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=UIMOJSHBVUUXAE-GOSISDBHSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-12 (MMP12) (Homo sapiens (Human))	BDBM50434222 (CHEMBL2385487) Show SMILES ONC(=O)[C@H]1CCCN1S(=O)(=O)CCc1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C19H22N2O4S/c22-19(20-23)18-7-4-13-21(18)26(24,25)14-12-15-8-10-17(11-9-15)16-5-2-1-3-6-16/h1-3,5-6,8-11,18,23H,4,7,12-14H2,(H,20,22)/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Florence Curated by ChEMBL					Assay Description Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assay				ACS Med Chem Lett 4: 565-9 (2013) Article DOI: 10.1021/ml300446a BindingDB Entry DOI: 10.7270/Q2B859HT
					More data for this Ligand-Target Pair