BDBM50434335 CHEMBL2386729::US9181275, 3
SMILES: C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=C(C)N2Cc3ccccc3CN=C2S1
InChI Key: InChIKey=QOLYCOJQUSUCGR-LJQANCHMSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50434335 (CHEMBL2386729 | US9181275, 3) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Binding affinity to histamine H3 receptor in rat cortical membranes | ACS Med Chem Lett 4: (2013) Article DOI: 10.1021/ml400105b BindingDB Entry DOI: 10.7270/Q2S75HQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H3 receptor (Rattus norvegicus (rat)) | BDBM50434335 (CHEMBL2386729 | US9181275, 3) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | 0.0200 | -14.6 | n/a | n/a | n/a | n/a | n/a | n/a | 25 |
AbbVie Inc. US Patent | Assay Description To determine the effectiveness of representative compounds of this invention as histamine-3 receptor ligands (H3 receptor ligands), the following tes... | US Patent US9181275 (2015) BindingDB Entry DOI: 10.7270/Q2R49PJP | |||||||||||
More data for this Ligand-Target Pair |