BDBM50434355 CHEMBL2386745
SMILES: COC(=N)c1nc2ccc3ncnc(Nc4ccc(F)cc4OC)c3c2s1
InChI Key: InChIKey=ZPXSIWLYMMFFCE-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual-specificity tyrosine-regulated kinases 1B (Homo sapiens (Human)) | BDBM50434355 (CHEMBL2386745) | UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.590 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of recombinant DYRK1B (unknown origin) after 120 mins in presence of [33P]-ATP | ACS Med Chem Lett 4: 502-3 (2013) Article DOI: 10.1021/ml400137s BindingDB Entry DOI: 10.7270/Q2NK3GDP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human)) | BDBM50434355 (CHEMBL2386745) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.360 | n/a | n/a | n/a | n/a | n/a | n/a |
Dart Neuroscience LLC Curated by ChEMBL | Assay Description Inhibition of recombinant DYRK1A (unknown origin) after 120 mins in presence of [33P]-ATP | ACS Med Chem Lett 4: 502-3 (2013) Article DOI: 10.1021/ml400137s BindingDB Entry DOI: 10.7270/Q2NK3GDP | |||||||||||
More data for this Ligand-Target Pair |