BDBM50434370 CHEMBL593252::GNF-Pf-3564::Thionin (14)

SMILES: Nc1ccc2nc3ccc(=[NH2+])cc3sc2c1

InChI Key: InChIKey=SHHZUHVSERGLNW-UHFFFAOYSA-O

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM50434370 (CHEMBL593252 | GNF-Pf-3564 | Thionin (14)) Show SMILES Nc1ccc2nc3ccc(=[NH2+])cc3sc2c1 Show InChI InChI=1S/C12H9N3S/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9/h1-6,13H,14H2/p+1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Humboldt-Universit£t zu Berlin Curated by ChEMBL					Assay Description Inhibition of tau protein aggregation (unknown origin) at 5:1 compound to protein concentration by Western blot analysis				J Med Chem 56: 4135-55 (2013) Article DOI: 10.1021/jm3017317 BindingDB Entry DOI: 10.7270/Q2HT2QQD
					More data for this Ligand-Target Pair
Microtubule-associated protein tau (TAU)(2N4R) (Homo sapiens (Human))	BDBM50434370 (CHEMBL593252 | GNF-Pf-3564 | Thionin (14)) Show SMILES Nc1ccc2nc3ccc(=[NH2+])cc3sc2c1 Show InChI InChI=1S/C12H9N3S/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9/h1-6,13H,14H2/p+1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	n/a
The Ohio State University					Assay Description The Tau content of fractions was determined by dot blot analysis using nitrocellulose membranes (0.2 μm porosity) as described previously [Cisek...				J Biol Chem 288: 32599-611 (2013) Article DOI: 10.1074/jbc.M113.503474 BindingDB Entry DOI: 10.7270/Q2R49PMK
					More data for this Ligand-Target Pair