BDBM50434766 CHEMBL2385812

SMILES: CC(C)C[C@H](NC(=O)Cn1ccc(cc1=O)N1CCOCC1)B(O)O

InChI Key: InChIKey=NSKXFGNFORKQEO-AWEZNQCLSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434766   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome component C5 (Homo sapiens (Human))	BDBM50434766 (CHEMBL2385812) Show SMILES CC(C)C[C@H](NC(=O)Cn1ccc(cc1=O)N1CCOCC1)B(O)O |r| Show InChI InChI=1S/C16H26BN3O5/c1-12(2)9-14(17(23)24)18-15(21)11-20-4-3-13(10-16(20)22)19-5-7-25-8-6-19/h3-4,10,12,14,23-24H,5-9,11H2,1-2H3,(H,18,21)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
					More data for this Ligand-Target Pair
20S proteasome chymotrypsin-like (Homo sapiens (Human))	BDBM50434766 (CHEMBL2385812) Show SMILES CC(C)C[C@H](NC(=O)Cn1ccc(cc1=O)N1CCOCC1)B(O)O |r| Show InChI InChI=1S/C16H26BN3O5/c1-12(2)9-14(17(23)24)18-15(21)11-20-4-3-13(10-16(20)22)19-5-7-25-8-6-19/h3-4,10,12,14,23-24H,5-9,11H2,1-2H3,(H,18,21)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Messina Curated by ChEMBL					Assay Description Inhibition of human 20S proteasome chymotrypsin like activity using Suc-Leu-Leu-Val-Tyr-AMC as substrate measured over 10 mins by fluorescence assay				Eur J Med Chem 64: 23-34 (2013) Article DOI: 10.1016/j.ejmech.2013.03.032 BindingDB Entry DOI: 10.7270/Q2S46TC8
					More data for this Ligand-Target Pair