BDBM50434922 CHEMBL2385418

SMILES: CC(C(=O)NCc1ccc(nc1OC1CCC(CC1)C(F)(F)F)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key: InChIKey=MANSNVFOMQIECA-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50434922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434922 (CHEMBL2385418) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCC(CC1)C(F)(F)F)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(13.52,-37.67,;13.52,-39.21,;12.19,-39.98,;12.19,-41.52,;10.86,-39.21,;9.52,-39.99,;8.19,-39.22,;8.18,-37.67,;6.85,-36.9,;5.52,-37.67,;5.52,-39.22,;6.85,-39.99,;6.86,-41.53,;5.51,-42.29,;4.19,-41.51,;2.85,-42.27,;2.83,-43.82,;4.17,-44.6,;5.52,-43.84,;1.5,-44.58,;.17,-43.8,;1.48,-46.12,;.16,-45.34,;4.19,-36.9,;4.19,-35.36,;2.85,-37.67,;2.85,-36.13,;14.86,-39.98,;14.85,-41.52,;16.19,-42.29,;17.52,-41.51,;18.86,-42.28,;20.19,-41.51,;21.52,-42.27,;19.4,-40.16,;20.94,-40.16,;17.51,-39.97,;18.84,-39.19,;16.18,-39.21,)| Show InChI InChI=1S/C24H26F7N3O4S/c1-13(14-3-9-19(18(25)11-14)34-39(2,36)37)21(35)32-12-15-4-10-20(24(29,30)31)33-22(15)38-17-7-5-16(6-8-17)23(26,27)28/h3-4,9-11,13,16-17,34H,5-8,12H2,1-2H3,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of capsaicin-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50434922 (CHEMBL2385418) Show SMILES CC(C(=O)NCc1ccc(nc1OC1CCC(CC1)C(F)(F)F)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 |(13.52,-37.67,;13.52,-39.21,;12.19,-39.98,;12.19,-41.52,;10.86,-39.21,;9.52,-39.99,;8.19,-39.22,;8.18,-37.67,;6.85,-36.9,;5.52,-37.67,;5.52,-39.22,;6.85,-39.99,;6.86,-41.53,;5.51,-42.29,;4.19,-41.51,;2.85,-42.27,;2.83,-43.82,;4.17,-44.6,;5.52,-43.84,;1.5,-44.58,;.17,-43.8,;1.48,-46.12,;.16,-45.34,;4.19,-36.9,;4.19,-35.36,;2.85,-37.67,;2.85,-36.13,;14.86,-39.98,;14.85,-41.52,;16.19,-42.29,;17.52,-41.51,;18.86,-42.28,;20.19,-41.51,;21.52,-42.27,;19.4,-40.16,;20.94,-40.16,;17.51,-39.97,;18.84,-39.19,;16.18,-39.21,)| Show InChI InChI=1S/C24H26F7N3O4S/c1-13(14-3-9-19(18(25)11-14)34-39(2,36)37)21(35)32-12-15-4-10-20(24(29,30)31)33-22(15)38-17-7-5-16(6-8-17)23(26,27)28/h3-4,9-11,13,16-17,34H,5-8,12H2,1-2H3,(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	6.0	n/a
Seoul National University Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHOK1 cells assessed as inhibition of pH 6 to 6.3-induced activity by FLIPR assay				Eur J Med Chem 64: 589-602 (2013) Article DOI: 10.1016/j.ejmech.2013.04.003 BindingDB Entry DOI: 10.7270/Q2BZ67FC
					More data for this Ligand-Target Pair