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SMILES: CCCOc1ccc(cc1)-c1cc(OCCN2CCC3(CC2)OCCO3)c2ccccc2n1

InChI Key: InChIKey=ICLBAZDUNRCWOX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50434967   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Quinolone resistance protein NorA


(Staphylococcus aureus)		BDBM50434967
PNG
(CHEMBL2385667)
Show SMILES CCCOc1ccc(cc1)-c1cc(OCCN2CCC3(CC2)OCCO3)c2ccccc2n1
Show InChI InChI=1S/C27H32N2O4/c1-2-16-30-22-9-7-21(8-10-22)25-20-26(23-5-3-4-6-24(23)28-25)31-17-15-29-13-11-27(12-14-29)32-18-19-33-27/h3-10,20H,2,11-19H2,1H3
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PC cid
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UniChem

Similars
Article
PubMed
n/an/a 8.50E+3n/an/an/an/an/an/a



Universit£ degli Studi di Perugia

Curated by ChEMBL


Assay Description
Inhibition of NorA in Staphylococcus aureus 1199B harboring grlA A116E mutant assessed as inhibition of ethidium bromide efflux measured for 5 mins b...

J Med Chem 56: 4975-89 (2013)


Article DOI: 10.1021/jm400262a
BindingDB Entry DOI: 10.7270/Q2765GRD
More data for this
Ligand-Target Pair