BDBM50435216 CHEMBL2392901

SMILES: COc1cccc(n1)-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1

InChI Key: InChIKey=BYIRXFDIJRLJDH-QFIPXVFZSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435216   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50435216 (CHEMBL2392901) Show SMILES COc1cccc(n1)-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1 |r| Show InChI InChI=1S/C27H34ClN7O2/c1-19-25(28)27(34-26(31-19)21-10-6-12-24(33-21)37-2)30-18-22(20-8-4-3-5-9-20)32-23(36)11-7-15-35-16-13-29-14-17-35/h3-6,8-10,12,22,29H,7,11,13-18H2,1-2H3,(H,32,36)(H,30,31,34)/t22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50435216 (CHEMBL2392901) Show SMILES COc1cccc(n1)-c1nc(C)c(Cl)c(NC[C@H](NC(=O)CCCN2CCNCC2)c2ccccc2)n1 |r| Show InChI InChI=1S/C27H34ClN7O2/c1-19-25(28)27(34-26(31-19)21-10-6-12-24(33-21)37-2)30-18-22(20-8-4-3-5-9-20)32-23(36)11-7-15-35-16-13-29-14-17-35/h3-6,8-10,12,22,29H,7,11,13-18H2,1-2H3,(H,32,36)(H,30,31,34)/t22-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair