BDBM50435218 CHEMBL2392899

SMILES: Cc1nc(nc(NC[C@H](NS(=O)(=O)CCN2CCNCC2)c2ccccc2)c1Cl)-c1ccccn1

InChI Key: InChIKey=QFUCQQDZDHXNRY-NRFANRHFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50435218   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human))	BDBM50435218 (CHEMBL2392899) Show SMILES Cc1nc(nc(NC[C@H](NS(=O)(=O)CCN2CCNCC2)c2ccccc2)c1Cl)-c1ccccn1 |r| Show InChI InChI=1S/C24H30ClN7O2S/c1-18-22(25)24(30-23(29-18)20-9-5-6-10-27-20)28-17-21(19-7-3-2-4-8-19)31-35(33,34)16-15-32-13-11-26-12-14-32/h2-10,21,26,31H,11-17H2,1H3,(H,28,29,30)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length cytosolic METAP1 expressed in Escherichia coli BL21(DE3) using Met-Pro-p-nitroanilide as substrate after ...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair
Microtubule-associated protein 2 (Homo sapiens (Human))	BDBM50435218 (CHEMBL2392899) Show SMILES Cc1nc(nc(NC[C@H](NS(=O)(=O)CCN2CCNCC2)c2ccccc2)c1Cl)-c1ccccn1 |r| Show InChI InChI=1S/C24H30ClN7O2S/c1-18-22(25)24(30-23(29-18)20-9-5-6-10-27-20)28-17-21(19-7-3-2-4-8-19)31-35(33,34)16-15-32-13-11-26-12-14-32/h2-10,21,26,31H,11-17H2,1H3,(H,28,29,30)/t21-/m0/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-6XHis-tagged full-length cytosolic METAP2 expressed in cabbage looper BTI-TN-5B1-4 cells using Met-Pro-p-nitroani...				Bioorg Med Chem 21: 2600-17 (2013) Article DOI: 10.1016/j.bmc.2013.02.023 BindingDB Entry DOI: 10.7270/Q290256X
					More data for this Ligand-Target Pair