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BDBM50435547 CHEMBL2392803

SMILES: Cc1cncn1CCCNC(=S)Nc1ccc2cnn(C)c2c1

InChI Key: InChIKey=LDJMNSUWNOEKDI-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM50435547
PNG
(CHEMBL2392803)
Show SMILES Cc1cncn1CCCNC(=S)Nc1ccc2cnn(C)c2c1
Show InChI InChI=1S/C16H20N6S/c1-12-9-17-11-22(12)7-3-6-18-16(23)20-14-5-4-13-10-19-21(2)15(13)8-14/h4-5,8-11H,3,6-7H2,1-2H3,(H2,18,20,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 239n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analys...


Bioorg Med Chem 21: 3821-30 (2013)


Article DOI: 10.1016/j.bmc.2013.04.005
BindingDB Entry DOI: 10.7270/Q2BR8TJF
More data for this
Ligand-Target Pair