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BDBM50435554 CHEMBL2392817

SMILES: Cc1cncn1CCCNC(=S)Nc1ccc2OCCOc2c1

InChI Key: InChIKey=DJEVZVHITAMVGR-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435554   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminyl Cyclase


(Homo sapiens (Human))
BDBM50435554
PNG
(CHEMBL2392817)
Show SMILES Cc1cncn1CCCNC(=S)Nc1ccc2OCCOc2c1
Show InChI InChI=1S/C16H20N4O2S/c1-12-10-17-11-20(12)6-2-5-18-16(23)19-13-3-4-14-15(9-13)22-8-7-21-14/h3-4,9-11H,2,5-8H2,1H3,(H2,18,19,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 58n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analys...


Bioorg Med Chem 21: 3821-30 (2013)


Article DOI: 10.1016/j.bmc.2013.04.005
BindingDB Entry DOI: 10.7270/Q2BR8TJF
More data for this
Ligand-Target Pair