BDBM50435558 CHEMBL2392814

SMILES: Cc1cncn1CCCNC(=S)Nc1ccc2OCCCc2c1

InChI Key: InChIKey=DCVTVEULPLNXDM-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminyl Cyclase (Homo sapiens (Human))	BDBM50435558 (CHEMBL2392814) Show SMILES Cc1cncn1CCCNC(=S)Nc1ccc2OCCCc2c1 Show InChI InChI=1S/C17H22N4OS/c1-13-11-18-12-21(13)8-3-7-19-17(23)20-15-5-6-16-14(10-15)4-2-9-22-16/h5-6,10-12H,2-4,7-9H2,1H3,(H2,19,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	208	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human glutaminyl cyclase expressed in HEK293 cells using L-glutaminyl-beta-naphthylamine as substrate after 1 hr by fluorometric analys...				Bioorg Med Chem 21: 3821-30 (2013) Article DOI: 10.1016/j.bmc.2013.04.005 BindingDB Entry DOI: 10.7270/Q2BR8TJF
					More data for this Ligand-Target Pair