BDBM50435578 CHEMBL2393132

SMILES: FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1

InChI Key: InChIKey=QWXMIWGVRDPXHK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50435578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human))	BDBM50435578 (CHEMBL2393132) Show SMILES FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C25H32F2N8O4/c26-21(27)22-28-20-18(2-1-3-19(20)39-17-6-32-4-11-36-12-5-32)35(22)25-30-23(33-7-13-37-14-8-33)29-24(31-25)34-9-15-38-16-10-34/h1-3,21H,4-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...				Eur J Med Chem 64: 137-47 (2013) Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33
					More data for this Ligand-Target Pair
p110α/p85α (Homo sapiens (Human))	BDBM50435578 (CHEMBL2393132) Show SMILES FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C25H32F2N8O4/c26-21(27)22-28-20-18(2-1-3-19(20)39-17-6-32-4-11-36-12-5-32)35(22)25-30-23(33-7-13-37-14-8-33)29-24(31-25)34-9-15-38-16-10-34/h1-3,21H,4-17H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr...				Eur J Med Chem 64: 137-47 (2013) Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33
					More data for this Ligand-Target Pair
p110β/p85α (Homo sapiens (Human))	BDBM50435578 (CHEMBL2393132) Show SMILES FC(F)c1nc2c(OCCN3CCOCC3)cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1 Show InChI InChI=1S/C25H32F2N8O4/c26-21(27)22-28-20-18(2-1-3-19(20)39-17-6-32-4-11-36-12-5-32)35(22)25-30-23(33-7-13-37-14-8-33)29-24(31-25)34-9-15-38-16-10-34/h1-3,21H,4-17H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra...				Eur J Med Chem 64: 137-47 (2013) Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33
					More data for this Ligand-Target Pair