BDBM50435580 CHEMBL2393144
SMILES: NCCOc1cccc2n(c(nc12)C(F)F)-c1nc(nc(n1)N1CCOCC1)N1CCOCC1
InChI Key: InChIKey=ZARNLYIBOHXAIJ-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoinositide 3-Kinase (PI3K), delta (Homo sapiens (Human)) | BDBM50435580 (CHEMBL2393144) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of recombinant PI3K p110delta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr... | Eur J Med Chem 64: 137-47 (2013) Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
p110α/p85α (Homo sapiens (Human)) | BDBM50435580 (CHEMBL2393144) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of recombinant PI3K p110alpha/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogr... | Eur J Med Chem 64: 137-47 (2013) Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
p110β/p85α (Homo sapiens (Human)) | BDBM50435580 (CHEMBL2393144) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland Curated by ChEMBL | Assay Description Inhibition of recombinant PI3K p110beta/p85alpha (unknown origin) using phosphotidylinositol as susbstrate after 1 hr by thin layer paper chromatogra... | Eur J Med Chem 64: 137-47 (2013) Article DOI: 10.1016/j.ejmech.2013.03.038 BindingDB Entry DOI: 10.7270/Q2377B33 | |||||||||||
More data for this Ligand-Target Pair |