BDBM50435922 CHEMBL2391270

SMILES: COc1ccc(Cc2cc(nn(CC(=O)Nc3ccc(Br)cc3)c2=O)-c2ccc(C)cc2)cc1

InChI Key: InChIKey=FOTFXRLBUSVZRA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FML2_HUMAN (Homo sapiens (Human))	BDBM50435922 (CHEMBL2391270) Show SMILES COc1ccc(Cc2cc(nn(CC(=O)Nc3ccc(Br)cc3)c2=O)-c2ccc(C)cc2)cc1 Show InChI InChI=1S/C27H24BrN3O3/c1-18-3-7-20(8-4-18)25-16-21(15-19-5-13-24(34-2)14-6-19)27(33)31(30-25)17-26(32)29-23-11-9-22(28)10-12-23/h3-14,16H,15,17H2,1-2H3,(H,29,32)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR3 (unknown origin) transfected in human HL60 cells assessed as induction of Ca2+ mobilization				Eur J Med Chem 64: 512-28 (2013) Article DOI: 10.1016/j.ejmech.2013.03.066 BindingDB Entry DOI: 10.7270/Q2N29ZBP
					More data for this Ligand-Target Pair