BDBM50435929 CHEMBL2391263

SMILES: COc1cccc(Cc2cc(nn(CC(=O)Nc3ccc(F)cc3)c2=O)-c2cccs2)c1

InChI Key: InChIKey=SQNPGQUQGQNXHK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FML2_HUMAN (Homo sapiens (Human))	BDBM50435929 (CHEMBL2391263) Show SMILES COc1cccc(Cc2cc(nn(CC(=O)Nc3ccc(F)cc3)c2=O)-c2cccs2)c1 Show InChI InChI=1S/C24H20FN3O3S/c1-31-20-5-2-4-16(13-20)12-17-14-21(22-6-3-11-32-22)27-28(24(17)30)15-23(29)26-19-9-7-18(25)8-10-19/h2-11,13-14H,12,15H2,1H3,(H,26,29)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR3 (unknown origin) transfected in human HL60 cells assessed as induction of Ca2+ mobilization				Eur J Med Chem 64: 512-28 (2013) Article DOI: 10.1016/j.ejmech.2013.03.066 BindingDB Entry DOI: 10.7270/Q2N29ZBP
					More data for this Ligand-Target Pair