BDBM50435933 CHEMBL2391259

SMILES: COc1cccc(Cc2cc(nn(CC(=O)Nc3ccc4OCOc4c3)c2=O)-c2ccccc2)c1

InChI Key: InChIKey=OMHHLYIMYPHLCD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50435933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
FML2_HUMAN (Homo sapiens (Human))	BDBM50435933 (CHEMBL2391259) Show SMILES COc1cccc(Cc2cc(nn(CC(=O)Nc3ccc4OCOc4c3)c2=O)-c2ccccc2)c1 Show InChI InChI=1S/C27H23N3O5/c1-33-22-9-5-6-18(13-22)12-20-14-23(19-7-3-2-4-8-19)29-30(27(20)32)16-26(31)28-21-10-11-24-25(15-21)35-17-34-24/h2-11,13-15H,12,16-17H2,1H3,(H,28,31)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Agonist activity at FPR3 (unknown origin) transfected in human HL60 cells assessed as induction of Ca2+ mobilization				Eur J Med Chem 64: 512-28 (2013) Article DOI: 10.1016/j.ejmech.2013.03.066 BindingDB Entry DOI: 10.7270/Q2N29ZBP
					More data for this Ligand-Target Pair