null

SMILES: C[C@]12CC[C@@H]3O[C@@H](OC[C@@]3(C)[C@@H]1C[C@H](OC(=O)c1ccc(cc1)C#N)[C@@]1(C)Oc3cc(oc(=O)c3[C@H](O)[C@H]21)-c1cccnc1)c1ccccc1F

InChI Key: InChIKey=ZIJYBRHNQICJRS-WVGFPPCDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50436348 (CHEMBL2398811) Show SMILES C[C@]12CC[C@@H]3O[C@@H](OC[C@@]3(C)[C@@H]1C[C@H](OC(=O)c1ccc(cc1)C#N)[C@@]1(C)Oc3cc(oc(=O)c3[C@H](O)[C@H]21)-c1cccnc1)c1ccccc1F |r| Show InChI InChI=1S/C40H37FN2O8/c1-38-15-14-30-39(2,21-47-37(50-30)25-8-4-5-9-26(25)41)29(38)18-31(49-35(45)23-12-10-22(19-42)11-13-23)40(3)34(38)33(44)32-28(51-40)17-27(48-36(32)46)24-7-6-16-43-20-24/h4-13,16-17,20,29-31,33-34,37,44H,14-15,18,21H2,1-3H3/t29-,30+,31+,33+,34-,37-,38+,39+,40-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of ACAT2 (unknown origin)				Bioorg Med Chem Lett 23: 3798-801 (2013) Article DOI: 10.1016/j.bmcl.2013.04.075 BindingDB Entry DOI: 10.7270/Q2WD41Z9
					More data for this Ligand-Target Pair
Sterol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50436348 (CHEMBL2398811) Show SMILES C[C@]12CC[C@@H]3O[C@@H](OC[C@@]3(C)[C@@H]1C[C@H](OC(=O)c1ccc(cc1)C#N)[C@@]1(C)Oc3cc(oc(=O)c3[C@H](O)[C@H]21)-c1cccnc1)c1ccccc1F |r| Show InChI InChI=1S/C40H37FN2O8/c1-38-15-14-30-39(2,21-47-37(50-30)25-8-4-5-9-26(25)41)29(38)18-31(49-35(45)23-12-10-22(19-42)11-13-23)40(3)34(38)33(44)32-28(51-40)17-27(48-36(32)46)24-7-6-16-43-20-24/h4-13,16-17,20,29-31,33-34,37,44H,14-15,18,21H2,1-3H3/t29-,30+,31+,33+,34-,37-,38+,39+,40-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Kitasato University Curated by ChEMBL					Assay Description Inhibition of ACAT1 (unknown origin)				Bioorg Med Chem Lett 23: 3798-801 (2013) Article DOI: 10.1016/j.bmcl.2013.04.075 BindingDB Entry DOI: 10.7270/Q2WD41Z9
					More data for this Ligand-Target Pair