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SMILES: OC(=O)COc1cccc(c1)C#Cc1c(oc2cc(O)c(cc12)C(O)=O)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=INKGMUYCBIXDMF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436365   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 22


(Homo sapiens (Human))		BDBM50436365
PNG
(CHEMBL2396716)
Show SMILES OC(=O)COc1cccc(c1)C#Cc1c(oc2cc(O)c(cc12)C(O)=O)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C26H15F3O8/c27-26(28,29)37-16-7-5-15(6-8-16)24-18(19-11-20(25(33)34)21(30)12-22(19)36-24)9-4-14-2-1-3-17(10-14)35-13-23(31)32/h1-3,5-8,10-12,30H,13H2,(H,31,32)(H,33,34)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Indiana University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...

J Med Chem 56: 4990-5008 (2013)


Article DOI: 10.1021/jm400248c
BindingDB Entry DOI: 10.7270/Q2N017XW
More data for this
Ligand-Target Pair