BDBM50436370 CHEMBL2396730

SMILES: OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=CIGQJLGCBGFBJN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50436370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50436370 (CHEMBL2396730) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C18H9F3O5/c1-2-11-12-7-13(17(23)24)14(22)8-15(12)25-16(11)9-3-5-10(6-4-9)26-18(19,20)21/h1,3-8,22H,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 294) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...				J Med Chem 56: 4990-5008 (2013) Article DOI: 10.1021/jm400248c BindingDB Entry DOI: 10.7270/Q2N017XW
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50436370 (CHEMBL2396730) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C18H9F3O5/c1-2-11-12-7-13(17(23)24)14(22)8-15(12)25-16(11)9-3-5-10(6-4-9)26-18(19,20)21/h1,3-8,22H,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...				J Med Chem 56: 4990-5008 (2013) Article DOI: 10.1021/jm400248c BindingDB Entry DOI: 10.7270/Q2N017XW
					More data for this Ligand-Target Pair