BDBM50436372 CHEMBL2396728

SMILES: OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=LLOLYYJHYGHTOY-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436372   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM50436372 (CHEMBL2396728) Show SMILES OC(=O)c1cc2c(C#C)c(oc2cc1O)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H14O4/c1-2-17-18-12-19(23(25)26)20(24)13-21(18)27-22(17)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h1,3-13,24H,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University School of Medicine Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged LYP catalytic domain (1 to 303) (unknown origin) expressed in Escherichia coli BL21(DE3) using pNPP as substrat...				J Med Chem 56: 4990-5008 (2013) Article DOI: 10.1021/jm400248c BindingDB Entry DOI: 10.7270/Q2N017XW
					More data for this Ligand-Target Pair