BDBM50436586 CHEMBL2397800

SMILES: Fc1cccc(Nc2ncnc3n(CC(Cl)c4ccccc4)ncc23)c1

InChI Key: InChIKey=GXIBVDBBEJEVPC-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50436586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50436586 (CHEMBL2397800) Show SMILES Fc1cccc(Nc2ncnc3n(CC(Cl)c4ccccc4)ncc23)c1 Show InChI InChI=1S/C19H15ClFN5/c20-17(13-5-2-1-3-6-13)11-26-19-16(10-24-26)18(22-12-23-19)25-15-8-4-7-14(21)9-15/h1-10,12,17H,11H2,(H,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Binding affinity to recombinant wild type human Abl using abitide as substrate				J Med Chem 56: 5382-94 (2014) Article DOI: 10.1021/jm400233w BindingDB Entry DOI: 10.7270/Q29G5P63
					More data for this Ligand-Target Pair